10th Annual Symposium
Physics of Cancer
Leipzig, Germany
September 25-27, 2019
 
P R E L I M I N A R Y   A G E N D A


Wednesday, 25th September 2019
 
11:00 – 13:00
Conference check-in and on-site registration
13:00 – 13:15
Opening | Welcome Words
13:15 – 13:45

Josef Käs (University of Leipzig, Germany)
10 years of Physics of Cancer
Session I: Cell mechanics
13:45 – 14:15
From molecular interactions to intermediate filament mechanics
Sarah Köster
Georg-August University Göttingen, Germany
14:15 – 14:45
Cell mechanics and cancer dissemination
Jochen Guck  
MPI for Physics of Light, Erlangen, Germany
14:45 – 15:00

Contributed talk 1
(t.b.a.)
15:00 – 15:30
Coffee break
15:30 – 16:00
3D shape transitions of active contractile sheets
Anne Bernheim
Ben Gurion University, Israel
16:00 – 16:30
Viscous dissipation in soft substrates affects focal adhesion formation,
cell morphology, and motility

Paul Janmey
University of Pennsylvania, USA
16:30 – 17:00
Viscoelastic properties of cell cortices - implications for cellular adhesion
Andreas Janshoff
Georg-August University Göttingen, Germany
17:00 – 17:15

Contributed talk 2
(t.b.a.)
17:30
Poster Session with Buffet Dinner | Young Scientist Awards

Thursday, 26th September, 2019
 

Session 2: Cancer cells and tumors in mechanical confinement
09:00 – 09:30
Mechanical heterogeneity in tissues promote rigidity and control cellular invasion
Dapeng Bi
Northeastern University, USA
09:30 – 10:00
Continuum theory of tissue dynamics
Frank Jülicher  
MPI for Physics of Complex Systems Dresden, Germany
10:00 – 10:30
3D microenvironment stiffness regulates
tumor spheroid growth and mechanics via p21 and ROCK

Anna Taubenberger
Technical University Dresden, Germany
10:15 – 11:00
Coffee break
11:00 – 11:30
3D motion of cancer cells in confined space
Timo Betz
University of Münster, Germany
11:30 - 12:00
Extracellular matrix stiffness and transforming growth factor-ß modulates
pancreatic stromal cells' cytoskeletal remodeling

Andreas Stylianou
University of Cyprus, Cyprus
12:00 – 12:30
(t.b.a.)
Kandice Tanner
National Cancer Institute, USA
12:30 – 13:30
Lunch buffet
Session 3: Tumor−stroma interaction 
13:30 – 14:00
Adhesion regulated mechanotransduction in cancer
Johanna Ivaska
University of Turku, Finland
14:00 – 14:30
Oxygen in cancer an neovascularization
Sharon Gerecht
Johns Hopkins University, USA
14:30 – 15:00
Organic and inorganic ECM components as synergistic regulators of cancer mechanosignaling
Claudia Fischbach-Teschl
Cornell University, USA
15:00 – 15:30
Addressing specific cell types with RNA
Rudolf Merkel
Forschungszentrum Jülich GmbH
Afternoon
Baroque concerto for all participants at "Alte Handelsbörse"
with "Camerata Bachiensis" 
Evening
Social Event for Invited Speakers 
(boat tour from city harbour to Restaurant "Stelzenhaus" & dinner)

Friday, 27th September, 2019
 

Session 4: Cellular mechanosensing
08:45 – 9:15
Adhesion G protein-coupled receptors - Metabotropic force sensors
that shape development and mechanosensation

Tobias Langenhan
University of Leipzig, Germany
9:15 – 09:45
EMT-induced cell mechanical changes enhance mitotic rounding strength
Elisabeth Fischer-Friedrich
Technical University Dresden, Germany
09:45 – 10:00

Contributed talk 3
(t.b.a.)
10:00 – 10:30
Nuclear rupture at high curvature and high rates leads to defects
in DNA repair to affect cell cycle, differentiation, and genome variation

Dennis Discher
University of Pennsylvania, USA
10:30 – 11:00
Coffee break
Session 5: Translational Research
11:00 – 11:30
Human tissue culture
Sonja Kallendrusch
University of Leipzig, Germany
11:30 – 12:00
Biophysical properties of tumors in vivo
Ingolf Sack
Charité Berlin, Germany
12:00 – 12:30
(t.b.a.)
Timm Denecke
University Hospital Leipzig, Germany
12:30 – 13:30
Lunch buffet
Session 6: Cancer cell migration
13:30 – 14:00
Dissecting cell migration and mechanics by systematic gene editing approaches
Klemens Rottner
Technical University Braunschweig, Germany
14:00 – 14:30
Mechanobiology of epithelial migration, growth and folding
Xavier Trepat
IBEC, Barcelona, Spain
14:30 – 15:00
Collective cell migration and viscoelasticity
Ivana Pajic-Lijakovic
University of Belgrade, Serbia
15:00 – 15:15

Contributed talk 4
(t.b.a.)
15:15 – 15:45
Coffee break
15:45 – 16:15
Confinement induces DNA damage causes increased matrix degradation
and invasiveness in duct carcinoma in situ breast cancer cells

Guilherme Nader
Institut Curié, France
16:15 – 16:45
Physical model for cellular self-polarization and
motility in one dimension: single cells and single-file chains

Nir Gov
Weizmann Institute of Science, Israel
16:45 – 17:15
Vimentin in cell mechanics and migration
Franziska Lautenschläger
Saarland University Saarbrücken, Germany
From 18:00 to open end:
Join the party at "Ratstonne" Mortizbastei with buffet and live music!

 

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