9th Annual Symposium
Physics of Cancer
Leipzig, Germany
September 24-26, 2018
P R E L I M I N A R Y   A G E N D A

Monday - September 24, 2018
11:00 – 13:00
Conference check-in and on-site registration
13:00 – 13:15
Opening | Welcome Words 
Session I: Cell Mechanics & Migration
13:15 – 13:45
The cancer-associated adhesion-protein ß-parvin functions as mechanoresponsive signaling hub that regulates cell size, shape, and contractility
Ingo Thievessen
(Friedrich Alexander University Erlangen-Nuremberg, Germany)
13:45 – 14:15
Feeling the tension: Cell-induced stresses in the extracellular matrix
Chase Broedersz 
(Ludwig Maximilians University Munich, Germany)
14:15 – 14:45
Role of phosphoinositide signaling in mechanoresponse of liver cancer cells
Paul Janmey
(University of Pennsylvania, USA)
14:45 – 15:00
Microenvironmental mechanics contribute to glioblastoma cell behaviour.
Katarzyna Pogoda
(Institute of Nuclear Physics Polish Academy of Sciences, Krakow, Poland)
15:00 – 15:30
Coffee break
15:30 – 16:00
Focal adhesion - hemidesmosome crosstalk in migrating keratinocytes
Rudolf Leube
(RWTH Aachen University, Germany)
16:00 – 16:30
Virtual fluidic channels: From single cell rheology to tissue mechanics
Oliver Otto
(University of Greifswald, Germany)
16:30 – 17:00
Polarized dynamics of intermediate filament in glial cell migration
Cécile Leduc
(The Institut Pasteur, France)
17:00 – 17:15
Mechanical cyclic stretching inhibits cancer cell growth but promotes normal cell growth
Ajay Tijore
(National University of Singapore, Singapore)
Welcome Dinner / Round Table

Tuesday - September 25, 2018

Session II: Membranes
09:00 – 09:30
Modulation of cortical actin assembly dynamics
Anne - Cécile Reymann
(Institute of Genetics and Molecular and Cellular Biology, France)
09:30 – 10:00
Physics of cell adhesion: The role of the membrane in the protein recognition process
Ana-Suncana Smith 
(Friedrich Alexander University Erlangen-Nuremberg, Germany)
10:00 – 10:15
Collective motion attenuates natural selection in crowded cellular populations
Jona Kayser
(University of California, Berkeley, USA)
10:15 – 10:45
Coffee break
Session III: Matrix
10:45 – 11:15
New peptide probes to map the tensional states of ECM fibers in tumor tissue
Viola Vogel
(ETH Zurich, Switzerland)
11:15 - 11:45
Mechanics matters for cells: From extracellular matrix via cytoskeleton to the nucleus
Florian Rehfeldt
(University of Göttingen, Germany)
11:45 – 12:15
Control of mechanosensitivity by integrin-ECM binding and nucleocytoplasmic shuttling kinetics
Pere Roca - Cusachs
(Institute for Bioengineering of Catalonia, Spain)
12:15 – 12:30
Biochemical and nanomechanical fingerprints of melanoma development
Justyna Bobrowska
(Polish Academy of Sciences, Kraków, Poland)
Poster Session 
12:30 – 15:00


Faculty of Physics and Earth Sciences
Linnéstr. 5, 04103 Leipzig

A snack buffet will be provided to go along with the poster session.

Social Event for Invited Speakers 
(private concert at Bach-museum, followed by dinner at "Ratskeller Leipzig")

Wednesday - September 26, 2018
Session IV: Vasculature
08:30 – 09:00
Search and kill - the immune response to cancer cells
Heiko Rieger
(Saarland University, Germany)
09:00 – 09:30
Probing the physiology of physical transport inside cells and developing tissues
Moritz Kreysing
(Max Planck Institute of Molecular Cell Biology and Genetics, Germany)
09:30 – 10:00
Mechanisms of cellular penetration of vascular basement membranes - how biophysics could help us better understand this process
Lydia Sorokin
(University of Münster, Germany)
10:00 – 10:15
Loss of vimentin increases motility and nuclear damage in confined spaces
Alison Patteson
(University of Pennsylvania, Philadelphia, USA)
10:15 – 10:45
Coffee break
Session V: Tissue Organization
10:45 - 11:15 
Ratchetaxis and cytokinesis
Daniel Riveline
(Institut de Génétique et de Biologie Moléculaire et Cellulaire, France)
11:15 – 11:45
PC3-Epi Prostate cancer cells become polyploid, resistant and
mesenchymal on a docetaxel gradient

Bob Austin
(Princeton University, USA)
11:45 – 12:15
Different modes of fluidization in human bronchial epithelial cells -- the unjamming transition vs. the epithelial-mesenchymal transition
Dapeng Bi 
(Northeastern University, USA)
12:15 – 12:30
Biomechanics of glioblastoma cells by atomic force microscopy
Tomasz Zielinski
(Polish Academy of Sciences, Kraków, Poland)
12:30 – 13:30
Session VI: Cancer and Embryology
13:30 – 14:00
Cancer resection within morphogenetic fields
Benjamin Wolf
(University Hospital Leipzig, Germany)
14:00 - 14:30
Coordination of tissue growth by cell mechanics
Maryam Aliee
(Friedrich-Alexander University of Erlangen-Nuremberg, Germany)
14:30 – 15:00
From non-linear dynamics to single-cell transcriptomics of cell state transitions
to preclinical studies

Sui Huang 
(Institute for Systems Biology, USA)
15:00 – 15:15
Collective forces of tumor spheroids in three-dimensional biopolymer networks
Christoph Mark
(Friedrich-Alexander University Erlangen-Nuremberg, Germany)
15:15 - 15:45
Coffee break
Session VII: Translational medicine
15:45 – 16:15
Catch me if you can: Circulating and disseminated tumor cells in breast cancer patients!
Bahriye Aktas
(University Hospital Leipzig, Germany)
16:15 – 16:45
Integrated optofluidic devices for cancer cell analysis and imaging
Roberto Osellame
(University of Milan, Italy)
Prospective End


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