|
|
IMPORTANT:
We will contact all virtual participants by email on Tuesday - October 3, 2023.
A G E N D A
Wednesday - October 4, 2023
| 09:30 – 11:30 |
Conference check-in |
| 11:30 – 11:45 |
Welcome |
| 11:45 – 12:15 |
Opening Talk
Accelerating the impact of cancer mechanopathology
Pep Pàmies
(Nature Biomedical Engineering) |
| Session I: Cancer cell and tissue mechanics I |
| 12:15 – 12:45 |
Quantifying intracellular mechanics by active and passive measurements
Timo Betz
(Georg-August University Göttingen, Germany) |
| 12:45 – 13:45 |
Lunch break |
| 13:45 – 14:15 |
Epithelial-mesenchymal transition and its influence on actin-cytoskeletal regulation
and cell proliferation
Elisabeth Fischer-Friedrich
(TU Dresden, Germany) |
| 14:15 – 14:30 |
Frictiotaxis underlies adhesion-independent durotaxis
Ricard Alert
(Max Planck Institute for the Physics of Complex Systems, Dresden, Germany) |
| 14:30 – 15:00 |
The effect of Ras oncogenes on cell mechanics
Helen Matthews
(University of Sheffield, UK) |
| 15:00 – 15:30 |
Coffee break |
| Session II: Cancer cell and tissue mechanics II |
| 15:30 – 16:00 |
Investigate the biomechanical traits of hepatocellular carcinoma with MRE
Jing Guo
(Charité Berlin, Germany) |
| 16:00 – 16:15 |
Tissue fluidification in pathophysiology: contact percolation sets phase transition and genetic rewiring in heterogeneous breast cancers
Leonardo Barzaghi
(The AIRC Institute of Molecular Oncology, Milan, Italy) |
| 16:15 – 16:45 |
Deformation of metabolically intact isolated nuclei
Paul Janmey
(University of Pennsylvania, USA) |
| 16:45 – 17:15 |
Heterogeneity of polarity and morphology in gastric cancer patient derived organoids
Natalie Dye
(TU Dresden, Germany) |
| 19:00 |
-CLASSICAL CONCERT FOR ALL-
Anna Elisabeth Hempel (Soprano),
Christian Hornef (Piano)
"Frauen im Leben" / "Women in Life"
at "Alte Börse" Leipzig
|
Thursday - October 5, 2023
| Session III: Cancer cell mechanobiology I |
| 09:00 – 09:30 |
Mechanobiology of intestinal organoids and tumoroids
Xavier Trepat
(IBEC Barcelona, Spain) |
| 09:30 – 09:45 |
Cluster formation of motile cells at the onset of cancer metastasis
Quirine J. S. Braat
(Eindhoven University of Technology, The Netherlands) |
| 09:45 – 10:15 |
Coffee break |
| 10:15 – 10:45 |
A mecano-biological feedback between cells and the ECM organizes
and sustains collective invasion
Marino Arroyo
(University of Barcelona, Spain) |
| 10:45 – 11:15 |
Feeling the force: molecular tools for quantifying cellular traction forces
Khalid Salaita
(Emory University, USA) |
| 11:15 – 13:00 |
Lunch break |
| 13:00 – 15:30 |
P O S T E R S E S S I O N
YOUNG SCIENTIST AWARDS
|
| 1 |
Frictiotaxis underlies adhesion-independent durotaxis
Ricard Alert
(Max Planck Institute for the Physics of Complex Systems, Dresden, Germany) |
| 2 |
Role of nuclear mechanics in the regulation of EMT in pancreatic cancer cells
Ona Baguer
(Institute for Bioengineering of Catalonia (IBEC), Barcelona, Spain) |
| 3 |
Tissue fluidification in pathophysiology: contact percolation sets phase transition and genetic rewiring in heterogeneous breast cancers
Leonardo Barzaghi
(The AIRC Institute of Molecular Oncology, Milan, Italy) |
| 4 |
Discovering physical parameters that influence cancer metastasis
Klara Beslmüller
(LACDR Leiden University, Leiden, The Netherlands) |
| 5 |
Cluster formation of motile cells at the onset of cancer metastasis
Quirine J. S. Braat
(Eindhoven University of Technology, The Netherlands) |
| 6 |
Mechanical characterization of migrating cancer cells in a 3D-1D tumor like model
I Chen
(University of Heidelberg, Germany) |
| 7 |
Electrodynamic Forces Driving DNA-Protein Interactions at Large Distance
Elham Faraji
(Forschungszentrum Jülich, Germany) |
| 8 |
Studying the mechanical and morphological phenotype of prostatic cancer-associated fibroblasts
Antje Garside
(TU Dresden, Germany) |
| 9 |
Analysis of biomechanical properties of healthy and cancerous prostate cells under normoxic and hypoxic growth conditions
Charlotte Gessinger
(Fraunhofer Zentrum für Mikroelektronische und Optische Systeme für die Biomedizin MEOS, Germany) |
| 10 |
State of Cell Unjamming correlates with distant Metastasis in Cancer Patients
Pablo Gottheil
(Leipzig University, Germany) |
| 11 |
Interaction of laminin and brain cells with ion implanted titania nanotube scaffolds
Jan Frenzel
(Leibniz Institute of Surface Engineering; Division of Biocompatible and Bioaktive Surfaces, Germany) |
| 12 |
Evaluation of physical and biological tumor characteristics in glioblastoma
Mani Sankari Kumaravadivel
(German Cancer Research Center (DKFZ), Germany) |
| 13 |
Deciphering the role of RAB5A-mediated tissue fluidification in cancer spheroid dynamics and their mechanical properties
Grégoire Lemahieu
(Max Planck Institute for Medical Research, Germany) |
| 14 |
Monitoring biophysical changes of tumor cells in confining 3D microenvironments: From single cells to multicellular structures
Vaibhav Mahajan
(TU Dresden, Germany) |
| 15 |
Force-biased nuclear import sets nuclear-cytoplasmic volumetric coupling by osmosis
Paolo Maiuri
(Federico II University of Naples, Italy) |
| 16 |
Immune cells employ intermittent integrin-mediated traction forces for 3D migration
Christoph Mark
(FAU Erlangen-Nuremberg, Germany) |
| 17 |
Mechanical properties of the premature lung
Jonas Naumann
(Leipzig University, Germany) |
| 18 |
Competition for space in tumors: Does dead matter matter?
Yoav G. Pollack
(University of Göttingen, Germany) |
| 19 |
Mechanosensing regulates immune killer cell-mediated immune surveillance
Bin Qu
(Saarland University, Germany) |
| 20 |
Viscoelastic properties of colorectal liver metastases reflect the tumor cell viability
Lisa-Marie Skrip
(Charité Berlin, Germany) |
| 21 |
Coarse-grained computational models of cancer metabolism and cellular growth
Ralf Steuer
(Humboldt University of Berlin, Germany) |
| 22 |
Tangential diffusion and motility-induced uncaging in growing spheroidal cell colonies
Torben Sunkel
(Max Planck Institute for Dynamics and Self-Organization, Göttingen, Germany) |
| 23 |
Identification of GB3 as a novel target for the alternative vasculature in neuroblastoma using a stiffness-based model
Aranzazu Villasante
(Institute for Bioengineering of Catalonia (IBEC), Spain) |
| 24 |
Vascularized neuroblastoma-on-a-chip
Aranzazu Villasante
(Institute for Bioengineering of Catalonia (IBEC), Spain) |
| 25 |
Surviving under pressure: mechano-metabolic regulation of cell density homeostasis
Kristina Havas
(IFOM ETS The AIRC Institute of Molecular Oncology, Italy ) |
| 26 |
Probing and analyzing the activity of brain organoids with advanced high-density microchip technology
Dennis Röhrig
(3Brain AG) |
| 27 |
Exploring the biophysical properties of hepatocellular carcinoma in an orthotopic mouse model through in vivo elastography
Pedro Augusto Dantas de Moraes
(Charité Universitätsmedizin Berlin, Germany) |
| Session IV: Cancer cell mechanobiology II |
| 15:30 – 16:00 |
Cancer cell migration through confined spaces: mechanisms and consequences
Jan Lammerding
(Cornell University, USA) |
| 16:00 – 16:30 |
Self-organizing principles driving tumor hierarchy and stemness
Carlos Perez-Gonzalez
(Institut Curie, France) |
| 16:30 – 16:45 |
Mechanosensing regulates immune killer cell-mediated immune surveillance
Bin Qu
(Saarland University, Germany) |
| 16:45 – 17:15 |
Understanding and exploiting cancer cell adhesion
Adam J. Engler
(UC San Diego, USA) |
| 17:15 – 17:45 |
Oxidative stress regulates talin mechanosensing
Sergi Garcia-Manyes
(King's College London, UK) |
| 18:30 |
S P E A K E R ‘S D I N N E R
(at "Café Cantona")
|
Friday - October 6, 2023
| Session V: Tumor cell dynamics I |
| 09:00 – 09:30 |
Effects of geometry on cell competition and survival at growing tumor edges
Maxim Lavrentovich
(Worcester State University, USA) |
| 09:30 – 10:00 |
Impact of cell adhesion during unjamming transition
Elisabeth Cavalcanti-Adam
(MPI Heidelberg, Germany) |
| 10:00 – 10:15 |
Force-biased nuclear import sets nuclear-cytoplasmic volumetric coupling by osmosis
Paolo Maiuri
(Federico II University of Naples, Italy) |
| 10:15 – 10:45 |
Controlling nuclear mechanics from the extracellular matrix and intermediate filaments
Pere Roca-Cusachs Soulere
(IBEC Barcelona, Spain) |
| 10:45 – 11:15 |
Coffee break |
| Session VI: Tumor cell dynamics II |
| 11:15 – 11:45 |
Chemo-mechanical diffusion waves orchestrate collective dynamics of immune and cancer cell podosomes
Vivek Shenoy
(University of Pennsylvania, USA) |
| 11:45 – 12:15 |
Cell migration and stromal fibroblasts sculpt patterns of cancer invasion, evolution, and therapy resistance
Erik Sahai
(Francis Crick Institute, UK) |
| 12:15 – 12:30 |
Coarse-grained computation models of cancer metabolism and cellular growth
Ralf Steuer
(Humboldt-University of Berlin, Germany) |
| 12:30 – 13:30 |
Lunch break |
| Session VII: Tumor microenvironment interactions I |
| 13:30 – 14:00 |
Biomaterials in cancer dormancy and early metastasis
Amaia Cipitria
(Biodonostia Health Research Institute, Spain) |
| 14:00 – 14:30 |
High resolution modeling of cell migration in the tumor immune ecosystem
Heiko Enderling
(MD Anderson Cancer Center, USA) |
| 14:30 – 14:45 |
Competition for space in tumors: Does dead matter matter?
Yoav G. Pollack
(University of Göttingen, Germany) |
| 14:45 – 15:15 |
Partial EMT versus unjamming, and their relevance for metastatic competence
Herbert Levine
(Northeastern University, USA) |
| 15:15 – 15:45 |
Coffee break |
| Session VIII: Tumor microenvironment interactions II |
| 15:45 – 16:15 |
Bulk tissue fluidity by in vivo MR elastography as a prognostic tumor marker
Ingolf Sack
(Charité Berlin, Germany) |
| 16:15 – 16:30 |
Identification of GB3 as a novel target for the alternative vasculature in neuroblastoma using a stiffness-based model
Aranzazu Villasante
(IBEC and BIST, Barcelona, Spain) |
| 16:30 – 17:00 |
Uncoupling cell responses from stiffness
Johanna Ivaska
(University of Turku, Finland) |
| 17:00 – 17:30 |
Overcoming a mechanical immune checkpoint for enhanced cancer immunotherapy
Li Tang
(EPFL Lausanne, Switzerland) |
|
