14th Annual Symposium Physics of Cancer Leipzig, Germany Oct. 4 - 6, 2023 |
PoC - Physics of Cancer - Annual Symposium |
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Invited Talk
Bulk tissue fluidity by in vivo MR elastography as a prognostic tumor marker
Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany
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Tissue mechanical properties measured by in vivo MR elastography have great potential for characterizing solid tumors in vivo. While increased tumor stiffness has long been known, it has limited prognostic value unless combined with solid stress measurements. Complementary to stiffening, cancer progression is accompanied by tissue fluidization, where parts of the tissue can change position over different length scales. This presentation will focus on the diagnostic potential of soft tissue fluidity as a diagnostic tumor marker in MR elastography. It will be discussed how tissue fluidity can be measured and to which tissue structures it relates in phantoms, healthy tissue and tumors.
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