13th "Physics of Cancer" Symposium

13th Annual Symposium
Physics of Cancer
Leipzig, Germany
Sept 28 - 30, 2022

PoC - Physics of Cancer - Annual Symposium

General Information

Scientific Program
Wednesday - September 28, 2022
Thursday - September 29, 2022
Friday - September 30, 2022

Postersession

Young Scientist Awards

Registration

Contribution

Location

Additional Information

Links & Sponsors

Impressions

Contact & Imprint

⇒agenda print version

A G E N D A

Wednesday - September 28, 2022

11:00 – 13:00 Conference check-in

13:00 – 13:15 Welcome

13:15 – 13:45 Opening Talk
Physics of Cancer - From Fundamental Biophysics to Translational Research
Cornelia Monzel
(Heinrich-Heine University Düsseldorf, Germany)

Session I: Cancer Immunotherapy

13:45 – 14:15 Genetic Engineering of Immune Effector Cells for Cancer Therapy
Helmut Hanenberg
(University Hospital Düsseldorf, Germany)

14:15 – 14:45 In and Out of Nanoparticles Into/Out of Cells
Wolfgang Parak
(University of Hamburg, Germany)

14:45 – 15:15 Differential Migration Mechanics and Immune Response of Glioblastoma Subtypes
David Odde
(University of Minnesota, USA)

15:15 – 15:30 On the Road to Cellular Digital Twins of in Vivo Tumors
Eric Behle
(Jülich Research Center, Germany)

15:30 – 16:00 Coffee break

16:00 – 16:30 Mechanistic and Mechanobiologic Principles of Immune and Cancer Cells 3D Motility Within Mechanically and Structurally Complex Microenvironments
Erdem D. Tabdanov
(University of Pennsylvania, USA)

16:30 – 1/:00 Flow, Deformation and Invasion of Tumor Spheroids on-a-Chip
Pouyan E. Boukany
(TU Delft, NL)

17:00 – 17:15 Nanotube Scaffolds: Versatile and Customizable Culture Platform for Cells and Tissues
Astrid Kupferer
(Leibniz Institute of Surface Engineering, Germany)

17:15 – 20:00
P O S T E R S E S S I O N
- onsite and virtual -

(including dinner buffet)

Thursday - September 29, 2022

Session II: Cancer Cell Migration and the Tumour Microenvironment
09:00 – 09:30	Tissue Fluidification Promotes a Pro-Inflammatory Transcriptional Response in Invasive Breast Carcinoma Fabio Giavazzi (Università degli Studi Di Milano, Italy)
09:30 – 10:00	A Positive Feedback Loop between Mesendoderm Cell Migration and Interstitial Fluid Relocalization is Required for Embryonic Axis Formation in Zebrafish Carl-Philipp Heisenberg (Institute of Science and Technology Austria, Austria)
10:00 – 10:15	Mapping Tumor Spheroid Mechanics in Dependence of 3D Microenvironment Stiffness and Degradability by Brillouin Microscopy Vaibhav Mahajan (TU Dresden, Germany)
10:15 – 10:45	Coffee break
10:45 – 11:15	Human 3D Vascularised Tumoroid Model for Glioblastoma Angiogenesis Athina Markaki (University of Cambridge, UK)
11:15 – 11:45	Self-Generated Gradients Steer Collective Migration on Viscoelastic Collagen Networks Andrew Clark (University of Stuttgart, Germany)
11:45 – 12:00	Physical Properties of 3D Matrix Regulate Killing Efficiency of Cytotoxic T Cells Bin Qu (Saarland University, Germany)
12:00 – 12:30	Control of Traction Forces, Force Propagation between Cells and Cell Migration by Optogenetics Ulrich Schwarz (Heidelberg University, Germany)
12:30 – 14:00	Lunch break
14:00 – 14:15	Distinct F-Actin Networks are Required for Filopodia Motility and Migration of Cancer Cells Sabine Windhorst (University Medical Center Hamburg-Eppendorf, Germany)
14:15 – 14:45	The Intersection of Mechanobiology and Cellular Metabolism in Cancer Cynthia Reinhart-King (Vanderbilt University, USA)
14:45 – 15:15	Coffee break
15:15 – 15:30	Single-Cell Physical Phenotyping of Mechanically Dissociated Tissue Biopsies for Fast Diagnostic Assessment Markéta Kubánková (Max Planck Institute for the Science of Light, Germany)
15:30 – 16:00	Centrosome Positioning and Re-Positioning in Immune Cells Heiko Rieger (Saarland University, Germany)
16:00 – 16:30	Biophysical Contributions of Adipose Tissue to Breast Cancer Invasion Adrian Shimpi and Garrett Beeghly (Cornell University, USA)
18:30	Social Event for Invited Speakers

Friday - September 30, 2022

Session III: Nanoagents for Targeted Cancer Cell Manipulation
09:00 – 09:15	Rigid Tumors Contain Soft Cells Thomas Fuhs (Technical University Freiberg, Germany)
09:15 – 09:45	Engineering Synthetic and Living Micro-and Nanoagents for Cancer Diagnosis and Therapy Simone Schürle-Finke (ETH Zurich, Switzerland)
09:45 – 10:15	Coffee break
10:15 – 10:45	Three-Dimensional Force Microscopy of Immune Cells in Biopolymer Networks Christoph Mark (Friedrich Alexander University Erlangen-Nuremberg, Germany)
10:45 – 11:15	Size, Force, Entropy at the Cellular Interface Young-wook Jun (University of California San Franciso, USA)
11:30 – 13:00	Lunch break
Session IV: Cell Mechanics in Cancer
13:00 – 13:30	Mapping the three-dimensional tumor microenvironment at single-cell resolution using CODA Denis Wirtz (Johns Hopkins University, USA)
13:30 – 14:00	The Keratin-Desmosome-Hemidesmosome Scaffold Rudolf Leube (University Hospital RWTH Aachen, Germany)
14:00 – 14:30	Structure and Assembly of Vimentin Intermediate Filaments Cécile Leduc (Institut Jacques Monod, France)
14:30 – 14:45	The Role of Intermediate Filaments in Stress Resistance in 3D Epithelial Structures Tom Golde (Institute of Bioengineering of Catalonia (IBEC), Spain)
14:45 – 15:15	High-Speed Atomic Force Microscopy and Scanning Ion Conductance Microscopy for Investigating the Mechanics and Dynamics of Cancer Cells Tilman E. Schäffer (Tübingen University, Germany)
15:15 – 15:45	Coffee break
15:45 – 16:15	Cancer Cell Invasion - Plasticity of Biomechanics in Response to Energy Deprivation Peter Friedl (The University of Texas, USA)
16:15 – 16:45	Biomechanical Tumor-Matrix Interactions in Breast Cancer Invasion Jacopo Ferruzzi (The University of Texas at Dallas, USA)