Invited Talk

In and Out of Nanoparticles Into/Out of Cells

Universität Hamburg, Institute for Nanostructure and Solid State Physics, Luruper Chaussee 149, 22761 Hamburg

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Examples will be presented on how colloidal nanoparticles can manipulate and investigate the interface between biology and materials science. This will involve characterization of protein adsorption, particle uptake by cells, fate of particles, and delivery and sensing applications. Special importance will be given to the discussion on how nanoparticles are endocytosed, and the subsequent loss of nanoparticles per cell due to proliferation and exocytosis. A description on how nanoparticles may be designed to favor different behavior will be given. Another focus will be on the discussion on how in vitro technology could be transferred to in vivo technology.