11th Annual Symposium
Physics of Cancer
Leipzig, Germany
September 22-24, 2020

We plan to use the software "Big Blue Button"


Tuesday - September 22, 2020
11:00 – 13:00
Conference check-in and on-site registration
13:00 – 13:15
Opening | Welcome Words
13:15 – 13:45
The mechano-chemical regulation of brain development and disease
Kristian Franze
University of Cambridge, United Kingdom
Session I
13:45 – 14:15
Impact of microtubule acetylation on mechanosensitive migration
Sandrine Etienne-Manneville
Institut Pasteur, France
14:15 – 14:30
Biomechanics of primary hippocampal neurons and SH-SY5Y cells in oxygen and glucose deprivation (OGD) model
Tomasz Zielinski
Polish Academy of Sciences, Poland
14:30 – 15:00
Dissecting asymmetric division of Drosophila neural stem cells by chemical genetics
Jens Januschke  
University of Dundee, Great Britain
15:00 – 15:30
Coffee break
Session II
15:30 – 16:00
YAP mechanosensing in the nucleus
Allen Ehrlicher
Mc Gill University, Canada
16:00 – 16:15
EMT-induced cell-mechanical changes enhance mitotic Rounding strength
Kamran Hosseini
TU Dresden, Germany
16:15 – 16:45
How does the extracellular matrix affect the rigidity of an embedded spheroid?
Jennifer M. Schwarz
Syracuse University, USA
16:45 – 17:15
Anomalous phase separation in co-cultures of cells with different mechanical properties
Moumita Das
Rochester Institute of Technology, USA

Wednesday - September 23, 2020

Session III
09:00 – 09:30
Investigating the role of the biomechanical microenvironment in determining response to anti-brain cancer therapies
Geraldine O`Neill
The University of Sydney, Australia
09:30 – 09:45
Intermediate filament heterogeneity and its role in the mechanics of glioblastoma invasion
Emma van Bodegraven
Institut Pasteur, France
09:45 – 10:15
Coffee break
10:15 – 10:45
Confined cell migration - a dynamical systems perspective
Chase Broedersz
LMU Munich, Germany
10:45 – 11:00
Optoregulated force application to individual cellular receptors using molecular motors
Mitchell Han
INM-Leibniz Institute for New Materials, Saarbrücken, Germany
11:00 – 13:00
Lunch break
13:00 – 15:30

Virtual Poster Session

Young Scientist Awards

Session IV
15:30 – 16:00
Viscoelastic properties of the isolated but metabolically intact nucleus
Paul Janmey
University of Pennsylvania, USA
16:00 – 16:30
Physical targeting strategies for enhanced therapeutic efficacy: bridging physics and biology through rational design
Sara Nizzero
Houston Methodist Hospital, USA
16:30 – 16:45
Elevation of keratin levels in reconstituted actin-keratin filament networks gradually increases their stress responsiveness
Iman Elbalasy
Leipzig University, Germany
16:45 – 17:15
Control of cell shape by vimentin intermediate filaments
Alison E. Patteson
Syracuse University, USA
17:15 – 17:45
Traction-independent cellular flows in cell aggregates
Michael Murrell
Yale University, USA

Thursday - September 24, 2020

Session V
09:00 – 09:30
Microtubules are sensory elements mediating feedback from integrin adhesions to the actomyosin cytoskeleton
Alexander Bershadsky
National University of Singapore, Singapore & Weizmann Institute of Science, Israel
09:30 – 10:00
Heterogeneity and plasticity of migratory cell behaviours
Alexandre Kabla
University of Cambridge, United Kingdom
10:00 – 10:15
Non-monotonic relation between cell speed and density in expanding 2D epithelia
Maxime Hubert
University of Erlangen-Nuremberg, Germany
10:15 – 10:45
Active nematic behavior of epithelial systems: a role in cell extrusion and cell sorting
Benoit Ladoux
Université Paris Diderot & Centre National de la Recherche Scientifique (CNRS), France
10:45 – 11:15
Coffee break
Session VI
11:15 – 11:45
How to interact: Investigation cell-substrate adhesion as a prerequisite to study tissue mechanics ex vivo
Mareike Zink
Leipzig University, Germany
11:45 – 12:15
Nanofibrous biopolymer scaffolds - from molecular mechanisms to new biomaterials
Dorothea Brüggemann
University of Bremen, Germany
12:15 – 12:30
Rapid modulation of filament mechanics by charge modifications
Julia Kraxner
University of Göttingen, Germany
12:30 – 13:30
Lunch buffet
Session VII
13:30 – 14:00
Jamming transitions of collective cancer cell invasion in 3D tissue
Peter Friedl
Radboud University, The Netherlands
14:00 – 14:30
Growth mechanics - coexistence and evolution
Jens Elgeti
Forschungszentrum Jülich, Germany
14:30 – 14:45
Synchronization of cellular forces in spheroids from primary breast tumor-associated mesenchymal cells
David Böhringer
Friedrich-Alexander University Erlangen-Nuremberg, Germany
14:45 – 15:15
Virtual fluidic channels: single cell rheology and tissue mechanics
Oliver Otto
University of Greifswald, Germany
15:15 – 15:45
Coffee break
Session VIII
15:45 – 16:15
Using CRISPR and TIRFM to Interrogate the in vivo Dynamics of Protein Complexes with Single Molecule Sensitivity
Ian G. Macara
Vanderbilt University, USA
16:15 – 16:30
Multiscale analysis reveals distinct cancer cell responses to environmental cues
Wolfgang Losert
University of Maryland, USA
16:30 – 17:00
Integrating evolutionary mathematical models into cancer therapy to increase the probability of control and cure
Robert Gatenby
Moffitt Cancer Center, USA
17:00 – 17:30
Direct evidence that tumor cells soften when navigating confined spaces
Sanjay Kumar
University of California, Berkeley, USA


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