11th "Physics of Cancer" Symposium

11th Annual Symposium
Physics of Cancer
Leipzig, Germany
September 22-24, 2020

PoC - Physics of Cancer - Annual Symposium

General Information

Scientific Program
Tuesday - September 22, 2020
Wednesday - September 23, 2020
Thursday - September 24, 2020

Young Scientist Awards

Registration

Contribution

Location

Additional Information

Links & Sponsors

Contact & Imprint

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Tuesday - September 22, 2020

11:00 – 13:00 Conference check-in and on-site registration

13:00 – 13:15 Opening | Welcome Words

13:15 – 13:45 The mechano-chemical regulation of brain development and disease
Kristian Franze
University of Cambridge, United Kingdom

Session I

13:45 – 14:15 Impact of microtubule acetylation on mechanosensitive migration
Sandrine Etienne-Manneville
Institut Pasteur, France

14:15 – 14:30 Biomechanics of primary hippocampal neurons and SH-SY5Y cells in oxygen and glucose deprivation (OGD) model
Tomasz Zielinski
Polish Academy of Sciences, Poland

14:30 – 15:00 Dissecting asymmetric division of Drosophila neural stem cells by chemical genetics
Jens Januschke
University of Dundee, Great Britain

15:00 – 15:30 Coffee break

Session II

15:30 – 16:00 YAP mechanosensing in the nucleus
Allen Ehrlicher
Mc Gill University, Canada

16:00 – 16:15 EMT-induced cell-mechanical changes enhance mitotic Rounding strength
Kamran Hosseini
TU Dresden, Germany

16:15 – 16:45 How does the extracellular matrix affect the rigidity of an embedded spheroid?
Jennifer M. Schwarz
Syracuse University, USA

16:45 – 17:15 Anomalous phase separation in co-cultures of cells with different mechanical properties
Moumita Das
Rochester Institute of Technology, USA

Wednesday - September 23, 2020

Session III
09:00 – 09:30	Investigating the role of the biomechanical microenvironment in determining response to anti-brain cancer therapies Geraldine O`Neill The University of Sydney, Australia
09:30 – 09:45	Intermediate filament heterogeneity and its role in the mechanics of glioblastoma invasion Emma van Bodegraven Institut Pasteur, France
09:45 – 10:15	Coffee break
10:15 – 10:45	Confined cell migration - a dynamical systems perspective Chase Broedersz LMU Munich, Germany
10:45 – 11:00	Optoregulated force application to individual cellular receptors using molecular motors Mitchell Han INM-Leibniz Institute for New Materials, Saarbrücken, Germany
11:00 – 13:00	Lunch break
13:00 – 15:30	Virtual Poster Session Young Scientist Awards
Session IV
15:30 – 16:00	Viscoelastic properties of the isolated but metabolically intact nucleus Paul Janmey University of Pennsylvania, USA
16:00 – 16:30	Physical targeting strategies for enhanced therapeutic efficacy: bridging physics and biology through rational design Sara Nizzero Houston Methodist Hospital, USA
16:30 – 16:45	Elevation of keratin levels in reconstituted actin-keratin filament networks gradually increases their stress responsiveness Iman Elbalasy Leipzig University, Germany
16:45 – 17:15	Control of cell shape by vimentin intermediate filaments Alison E. Patteson Syracuse University, USA
17:15 – 17:45	Traction-independent cellular flows in cell aggregates Michael Murrell Yale University, USA

Thursday - September 24, 2020

Session V
09:00 – 09:30	Microtubules are sensory elements mediating feedback from integrin adhesions to the actomyosin cytoskeleton Alexander Bershadsky National University of Singapore, Singapore & Weizmann Institute of Science, Israel
09:30 – 10:00	Heterogeneity and plasticity of migratory cell behaviours Alexandre Kabla University of Cambridge, United Kingdom
10:00 – 10:15	Non-monotonic relation between cell speed and density in expanding 2D epithelia Maxime Hubert University of Erlangen-Nuremberg, Germany
10:15 – 10:45	Active nematic behavior of epithelial systems: a role in cell extrusion and cell sorting Benoit Ladoux Université Paris Diderot & Centre National de la Recherche Scientifique (CNRS), France
10:45 – 11:15	Coffee break
Session VI
11:15 – 11:45	How to interact: Investigation cell-substrate adhesion as a prerequisite to study tissue mechanics ex vivo Mareike Zink Leipzig University, Germany
11:45 – 12:15	Nanofibrous biopolymer scaffolds - from molecular mechanisms to new biomaterials Dorothea Brüggemann University of Bremen, Germany
12:15 – 12:30	Rapid modulation of filament mechanics by charge modifications Julia Kraxner University of Göttingen, Germany
12:30 – 13:30	Lunch buffet
Session VII
13:30 – 14:00	Jamming transitions of collective cancer cell invasion in 3D tissue Peter Friedl Radboud University, The Netherlands
14:00 – 14:30	Growth mechanics - coexistence and evolution Jens Elgeti Forschungszentrum Jülich, Germany
14:30 – 14:45	Synchronization of cellular forces in spheroids from primary breast tumor-associated mesenchymal cells David Böhringer Friedrich-Alexander University Erlangen-Nuremberg, Germany
14:45 – 15:15	Virtual fluidic channels: single cell rheology and tissue mechanics Oliver Otto University of Greifswald, Germany
15:15 – 15:45	Coffee break
Session VIII
15:45 – 16:15	Using CRISPR and TIRFM to Interrogate the in vivo Dynamics of Protein Complexes with Single Molecule Sensitivity Ian G. Macara Vanderbilt University, USA
16:15 – 16:30	Multiscale analysis reveals distinct cancer cell responses to environmental cues Wolfgang Losert University of Maryland, USA
16:30 – 17:00	Integrating evolutionary mathematical models into cancer therapy to increase the probability of control and cure Robert Gatenby Moffitt Cancer Center, USA
17:00 – 17:30	Direct evidence that tumor cells soften when navigating confined spaces Sanjay Kumar University of California, Berkeley, USA