8th Annual Symposium
Physics of Cancer
Leipzig, Germany
October 4-6, 2017

PoC Booklet
(PDF, 87 KByte)


All talk sessions take place at Max Planck Institute for Evolutionary Anthropology.
Invited talks are scheduled 20 min plus 10 min discussion.
Contributed talks are allocated 15 min including discussion.


The session for poster presentation takes place at the Centre for Biotechnology and Biomedicine
on October 5, 2017. During this session, there will be a snack buffet for all participants.


On October 4, 2017 we would like to invite you to take part in our Welcome Dinner.
Prepare for good conversation and food - we are looking forward to meeting you!
Assembly Hall of the Faculty of Physics and Earth Sciences,
Linnéstr. 5, 04103 Leipzig, first floor,

P R E L I M I N A R Y   A G E N D A

Wednesday - October 4, 2017
11:00 – 13:00
Conference check-in and on-site registration
13:00 – 13:15
Opening | Welcome Words by Mayor of Leipzig
Session I: Cell Migration & Invasion
13:15 – 13:45
Slice Cultures as Tool to Study Cancers in Vitro
Ingo Bechmann 
(University of Leipzig, Germany)
13:45 – 14:15
Hybrid Epithelial/Mesenchymal Phenotype (E/M) – a ‘Metastatic Sweet Spot’
Mohit Kumar Jolly 
(Rice University, USA)
14:15 – 14:45
Control of Cancer Cell Invasion by Nuclear Deformability 
Katarina Wolf 
(Radboud Institute for Molecular Life Sciences, The Netherlands)
14:45 – 15:00
High Shear Stresses under Exercise Condition Destroy Circulating Tumor Cells 
in a Microfluidic System
Sagar Regmi
(Nanyang Technological University, Singapore)
15:00 – 15:30
Matrix Adhesion Site Function in Polarised Invasive Migration
Tobias Zech
(University of Liverpool, GB)
15:30 – 16:00
Coffee break
Special Focus Session: Collective Cell Behavior
16:00 – 16:30
Control of Mechanochemical Self-Organization during Cell Polarization
Stephan Grill 
(Technical University Dresden, Germany)
16:30 – 17:00
Physical Forces Driving Migration, Division and Folding of Epithelial Sheets
Xavier Trepat 
(IBEC Barcelona, Spain)
17:00 – 17:15
Mechanisms of Collective Cell Migration and the Influence of the Microenvironment
Andrew Clark
(Institute Curie, France)
17:15 – 17:45
Unjamming and Cell Shape Changes in Breast Cancer
Jae Hun Kim
(Harvard T.H. Chan School of Public Health, USA)
17:45 – 18:15
Tissue Surface Tension in Simple Models of Dense Biological Tissues
Daniel Sussman
(Syracuse University, USA)
Welcome Dinner 

Thursday - October 5, 2017

Session II: Biomechanics
08:15 – 08:30
Guiding 3D Cell Migration inside Strained Synthetic Hydrogel Micro-Structures
Miriam Dietrich
(Ludwig-Maximilians-University, Germany)
08:30 – 09:00
The Weakness of Senescent Fibroblasts
Kay Gottschalk 
(University of Ulm, Germany)
09:00 – 09:30
Squish and Squeeze – the Role of the Nucleus and Lamins in Cancer Metastasis
Jan Lammerding 
(Cornell University, USA)
09:30 – 10:00
Interactions of Natural Killer Cells with Cancer Cells in a 3-D Environment
Ben Fabry 
(Friedrich-Alexander University of Erlangen-Nuremberg, Germany)
10:00 – 10:30
Coffee break
10:30 – 11:00
Integrating Scales in Cancer Mechanobiology: The NCI Physical Sciences – Oncology Network
Nastaran Zahir
(National Cancer Institute, USA)
11:00 - 11:15
Light Sheet Fluorescence Microscopy: Advantages for Living Specimens
Ulf-Dietrich Braumann
(Fraunhofer Institute for Cell Therapy and Immunology, Germany)
11:15 – 11:45
From “CAR T Cells” to CAR Expressing NK Cells for Cancer Retargeting
Ulrike Köhl
(Hannover Medical School, Germany)
11:45 – 12:15
Collectively Emerging Nematic Order in Populations of Fibroblasts
Pascal Silberzan
(Institut Curie Paris, France) 
12:15 – 12:30
Disrupting Chemotaxis Using Contact Guidance of Nanotopography
Sebastian Schmidt
(University of Maryland, USA)
Poster Session
12:30 – 15:00
- Presentation of contributed posters with discussions 
and lunch buffet -
Social Event for Invited Speakers 
(guided tours "St. Thomas Church" and "Bach Museum", followed by dinner)

Friday - October 6, 2017
Session III: Cellular Organization
Convergent Science Physical Oncology by IOP Publishing
08:15 – 08:30
Non-Linear Compliance of Elastic Layers to Indentation
Adrian Fessel
(University of Bremen, Germany)
08:30 – 09:00
Mechanotransduction in Collective Cell Migration
Joachim Spatz 
(Max Planck Institute for Medical Research and University of Heidelberg, Germany)
09:00 – 09:30
Of Active Motors and Passive Crosslinker: Reconstituting Adaptive Microtubule Networks
Stefan Diez
(Technical University Dresden, Germany)
09:30 – 10:00
Multiscale Cell Motility: From Substrate Deformation to Collective Migration 
Erwin Frey
(Ludwig-Maximilians-University Munich, Germany)
10:00 – 10:30
Coffee break
10:30 – 11:00
Emergent Cancer-like Phenomenology in a Simple Model of Cells with Growth and Chemical Signalling
Ramin Golestanian
(University of Oxford, UK)
11:00 - 11:15 
Electron Irradiated Hydrogels: Reagent-Free Modification towards Biomedical Applications
Stefanie Riedel
(Leibniz Institute of Surface Modification, Germany)
11:15 – 11:45
Establishing Nuclear Subcompartments and Chromatin Patterns to Regulate Gene Expression 
Karsten Rippe
(German Cancer Research Center Heidelberg, Germany)
11:45 – 12:15
Strain-Controlled Rigidity Transitions in Cells and the Role of the Cell Nucleus
Jennifer Schwarz 
(Syracuse University, USA)
12:15 – 12:45
Physicochemical Properties of Basement Membranes Formed by a Cell Culture Model of Human Breast Glands
Rudolf Merkel
(Forschungszentrum Jülich, Germany)
13:00 – 14:00
Session IV: Tissue Organization
14:00 – 14:30
Morphology Control by Active Fluid Flows
Karen Alim
(Max Planck Institute for Dynamics and Self-Organization Göttingen, Germany)
14:30 - 14:45
An Intriguing Similarity between Cancer Metastasis and Financial Markets
Christoph Mark
(Friedrich-Alexander University of Erlangen-Nuremberg, Germany)
14:45 – 15:15
Ana-Suncana Smith 
(Friedrich-Alexander University of Erlangen-Nuremberg, Germany)
15:15 – 15:45
Physical Aspects of Successful Cell Circulation and Migration
Jochen Guck 
(Technical University Dresden, Germany)
15:45 - 16:15
Coffee break
16:15 – 16:45
Mapping Cadherin-Dependent Cell Adhesion and Elasticity Changes in Tissue Explants during the Transition from Collective to Single-Cell Migration
Clemens Franz
(Karlsruhe Institute of Technology, Germany)
16:45 – 17:15
Regulation of Actin Cytoskeleton during Epithelial to Mesenchymal Transition - The Ocular Lens Perspective
Aftab Taiyab
(McMaster University, Canada)
17:15 - 17:45
In Situ Mechanobiology of Epithelia in Health and Disease
Marija Plodinec 
(University Center Basel, Switzerland)
Prospective End


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