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A G E N D A
Wednesday - September 25, 2019
| 11:00 – 13:00 |
Conference check-in and on-site registration |
| 13:00 – 13:15 |
Opening | Welcome Words |
| 13:15 – 13:45 |
Cell and tissue mechanics in solid tumors: Hype or progress?
Josef Käs
Leipzig University, Germany |
| Session I: Cell mechanics |
| 13:45 – 14:15 |
From molecular interactions to intermediate filament mechanics
Sarah Köster
Georg-August University Göttingen, Germany |
| 14:15 – 14:45 |
Cell mechanics and cancer dissemination
Jochen Guck
TU Dresden & MPI for Physics of Light, Erlangen, Germany |
| 14:45 – 15:00 |
Mechanobiological control of Circular Dorsal Ruffle dynamics
Hans-Günther Döbereiner
University of Bremen, Germany |
| 15:00 – 15:30 |
Coffee break |
| 15:30 – 16:00 |
3D shape transitions of active contractile sheets
Anne Bernheim
Ben Gurion University, Israel |
| 16:00 – 16:30 |
Viscous dissipation in soft substrates affects focal adhesion formation,
cell morphology, and motility
Paul Janmey
University of Pennsylvania, USA |
| 16:30 – 17:00 |
Viscoelastic properties of cell cortices - implications for cellular adhesion
Andreas Janshoff
Georg-August University Göttingen, Germany |
| 17:00 – 17:15 |
Tumor heterogeneity - a possible mechanical origin
Tobias Büscher
Forschungszentrum Jülich GmbH |
| 17:30 |
Poster Session with Buffet Dinner |
Young Scientist Awards
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Thursday - September 26, 2019
Friday - September 27, 2019
| Session 4: Cellular mechanosensing |
| 08:45 – 9:15 |
Adhesion G protein-coupled receptors - Metabotropic force sensors
that shape development and mechanosensation
Tobias Langenhan
Leipzig University, Germany |
| 9:15 – 09:45 |
EMT-induced cell mechanical changes enhance mitotic rounding strength
Elisabeth Fischer-Friedrich
TU Dresden, Germany |
| 09:45 – 10:00 |
MITF-mediated changes of tumour architecture, tensile stress and in extracellular matrix (ECM) control intratumour heterogeneity in melanoma models
Loredana Spoerri
The University of Queensland, Brisbane, Australia |
| 10:00 – 10:30 |
Nuclear rupture at high curvature and high rates leads to defects
in DNA repair to affect cell cycle, differentiation, and genome variation
Dennis Discher
University of Pennsylvania, USA |
| 10:30 – 11:00 |
Coffee break |
| Session 5: Translational research |
| 11:00 – 11:30 |
Human tissue culture
Sonja Kallendrusch
Leipzig University, Germany |
| 11:30 – 12:00 |
Biophysical properties of tumors in vivo
Ingolf Sack
Charité Berlin, Germany |
| 12:00 – 12:15 |
Collective motion promotes multi-step drug resistance evolution in dense cellular populations
Jona Kayser
University of California, Berkeley, USA |
| 12:15 – 13:30 |
Lunch buffet |
| Session 6: Cancer cell migration |
| 13:30 – 14:00 |
Dissecting cell migration and mechanics by systematic gene editing approaches
Klemens Rottner
Technical University Braunschweig, Germany |
| 14:00 – 14:30 |
Mechanobiology of epithelial migration, growth and folding
Xavier Trepat
IBEC, Barcelona, Spain |
| 14:30 – 15:00 |
Collective cell migration and viscoelasticity
Ivana Pajic-Lijakovic
University of Belgrade, Serbia |
| 15:00 – 15:15 |
Strategies for individual and collective cell migration by heterogeneous cell populations during cancer metastasis
Parag Katira
San Diego State University, San Diego, USA |
| 15:15 – 15:45 |
Coffee break |
| 15:45 – 16:15 |
Confinement induces DNA damage causes increased matrix degradation
and invasiveness in duct carcinoma in situ breast cancer cells
Guilherme Nader
Institut Curié, France |
| 16:15 – 16:45 |
Physical model for cellular self-polarization and
motility in one dimension: single cells and single-file chains
Nir Gov
Weizmann Institute of Science, Israel |
| 16:45 – 17:15 |
Vimentin provides the mechanical resilience required for amoeboid migration and protection of the nucleus
Franziska Lautenschläger
Saarland University Saarbrücken, Germany |
From 18:00 to open end:
Join the party at "Ratstonne" Moritzbastei with buffet and live music! |
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