Additionally, all participant will receive a printed program booklet. You may also download this program booklet as PDF file. 

Talks:
All talk sessions take place in the large auditory (ground floor, SR 1.1 to 1.3) of the Center for Biotechnology and Biomedicine (BBZ). Contributed talks are allocated 15 min (including discussion), whereas invited talks are allocated 20 min plus 10 min discussion.

Posters:
The session for poster presentation takes place in the foyer of the Center for Biotechnology and Biomedicine (BBZ). During this session, there will be a snack buffet for all participants. The poster boards will be marked with the number according to the scientific program. Posters must fit within a rectangle 90 cm wide and 120 cm high (DIN A0), portrait format. The material necessary to mount the poster (pins or "Poster Strips") will be provided.

 

11:00 – 13:00	Conference check-in and on-site registration
13:00 – 13:15	Welcome and opening Josef A. Käs (University of Leipzig, Germany)
Session I: Mechanical properties of cancer cells I
13:15 – 13:45	Mechanical sensing by normal and transformed cells Paul Janmey (University of Pennsylvania, USA)
13:45 – 14:15	Individual and collective metastatic cell migration behaviors Cynthia Reinhart-King (Cornell University, USA)
14:15 – 14:45	Applying controlled mechanical pressure on tumor cells aggregates Giovanni Cappello (Institut Curie, France)
14:45 – 15:15	Coffee break
15:15 – 15:45	Mechanical constraints and cancer Daniel Fletcher (University of California, Berkeley, USA)
15:45 – 16:15	Early changes in tissue organisation and structure in colorectal cancer Inke Näthke (University of Dundee, UK)
16:15 – 16:45	Biomechanical processes and topological dynamics in tumors Lance L. Munn (Massachusetts General Hospital & Harvard Medical School, USA)
16:45 – 17:15	Caveolae-mediated mechanotransduction in single cells and imaging of confined spheroids Franziska Wetzel (Institut d'Optique Graduate School, France)
17:15 – 17:30	Biomechanics of human primary tissue cells in tumor progression Anatol Fritsch (University of Leipzig, Germany)
17:30 – 17:45	Cell deformability during passage through micron-scale constrictions Janina Lange (University of Erlangen-Nuremberg, Germany)
17:45 – 18:00	Epithelial closure dynamics Philippe Marcq (Institut Curie, France)
Evening	Enjoy the evening at your own disposal.

 

Session II: Membranes and the cytoskeleton
08:30 – 09:00	Pulling with filopodia: high forces on weak connections Patricia Bassereau (Institut Curie, France)
09:00 – 09:30	Oncogenic signaling and the cytoskeleton David M. Helfman (KAIST, South Korea)
09:30 – 10:00	Mechanism of CD95 clustering and activation at the single cell level Joel Beaudouin (German Cancer Research Center & BioQuant, Germany)
10:00 – 10:30	Mimicking tissues with densely packed lipid droplets Jasna Brujic (New York University, USA)
10:30 – 11:00	Coffee break
11:00 – 11:30	The mechanics of invasion: How contraction sets the stage for invasive migration Timo Betz (Institut Curie, France)
11:30 – 12:00	Chemomechanics of cell migration and activation in the cancer microenvironment Krystyn J. van Vliet (Massachusetts Institute of Technology, USA)
12:00 – 12:30	Oncogenic cell transformation changes the nanoscale organization of adhesions, vimentin filaments and cell stiffness Annica K. B. Gad (Karolinska Institutet, Sweden)
12:30 – 12:45	The role of vimentin in cell migration under confinement Luiza Stankevicins (Saarland University, Germany)
12:45 – 13:00	Cancer cell behaviours on a culture substrate imprinted with their own features Tiffany Tan (University of Otago, New Zealand)
13:00 – 14:30	Lunch
Afternoon	Get-together with visit to the museum “Zeitgeschichtliches Forum” (free admission).  For all invited speakers, there will be a guided tour starting at 16:00.  (Please note that October 3 is a national holiday in Germany. Hence, most shops will be closed.)
18:00	Motet at St. Thomas church (2.00 EUR admission). Note that doors already open at  17:15. No reservations possible. Free admission for all invited speakers.
19:00	Dinner at "Auerbachs Keller" for all invited speakers

 

Session III: Mechanical properties of cancer cells II
08:30 – 09:00	Analysis of a few in vitro experiments Jacques Prost (Institut Curie, France)
09:00 – 09:30	Mechanotransduction in developing cell systems Kristian Franze (University of Cambridge, UK)
09:30 – 10:00	Association between embryonic development and locoregional cancer progression Michael Höckel (University of Leipzig, Germany)
10:00 – 10:30	Coffee break
10:30 – 11:00	Biophysical characterization of the myxobacterial compound Soraphen A: an innovative option to fight invasive cancer Angelika M. Vollmar (LMU Munich, Germany)
11:00 – 11:30	Actin-based transport adapts polar cap size to local curvature Daria Bonazzi (Institut Jacques Monod, France)
11:30 – 12:00	Modeling glioma and targeting the glioma niche Karin Forsberg Nilsson (Uppsala University, Sweden)
12:00 – 12:15	Is cell segregation governed by cellular adhesion? Steve Pawlizak (University of Leipzig, Germany)
12:15 – 12:30	Mesenchymal migration cannot be described as a persistent random walk Charlotte Riviere (Université Lyon 1, France)
12:30 – 14:30	Lunch break
Session IV: Microtools for study and diagnostics in cancer research
14:30 – 15:00	Measuring cell mechanics for medicine Dino Di Carlo (University of California, Los Angeles, USA)
15:00 – 15:30	Quantifying metastasis using rare events Timothy Newman (University of Dundee, UK)
15:30 – 16:00	Plasticity of cancer cell migration: Extracellular matrix enables the optimisation of blebbing, adhesions, and spreading Melda Tozluoglu (University College London, UK)
16:00 – 16:15	New elasticity-patterned substrates for bi-dimensional organization of cells Camille Migdal (iRTSV, CEA Grenoble, France)
16:15 – 16:30	Emergence of collective cell migration on circular micropatterns Felix Jakob Segerer (Ludwig Maximilian University of Munich, Germany)
16:30 – 17:00	Coffee break
17:00 – 17:30	Micromechanical tools to study the role of vimentin in cells Franziska Lautenschläger (Saarland University, Germany)
17:30 – 18:00	Role of serum response factor in the mechanotransduction of myoblasts Sylvie Hénon (Université Paris Diderot, France)
Poster Session
19:00 – 22:00	During the poster session, there will be a snack buffet for all participants.
	01	Intracellular stresses in patterned cell assemblies Alice Nicolas (Université Joseph Fourier, France)
	02	Modulation of membrane rigidity impacts cell migration and invasion Sebastian Schmidt (University of Leipzig, Germany)
	04	The interactions of hERG1 potassium channels and ß1 integrins in pancreatic ductal adenocarcinoma cells Stefano Coppola (Sapienza University of Rome, Italy)
	05	Mechanical cues in Ewing sarcoma metastasis Elena Beletkaia (Leiden University, The Netherlands)
	06	Plasma membrane softening in human breast and cervical cancer cells Chris Händel (University of Leipzig, Germany)
	07	The native root extract of Linum usitatissimum: stress fiber induction by increased profilin-1 expression results in reduced motility of MCF-7 breast cancer cells Nadja Engel-Lutz (University Medical Center Rostock, Germany)
	08	Mechanosensation in Constrained Collagen Matrices Hamid Mohammadi (University of Toronto, Canada)
	09	Heterogeneity and dynamics of cancer cells at the interface of step-gradients of 3D collagen matrices Jiranuwat Sapudom (University of Leipzig, Germany)
	10	Biophysical method for early cancer detection Jelena Muncan (University of Belgrade, Serbia)
	11	Contractile actin bundle without molecular motors Jörg Schnauß (University of Leipzig, Germany)
	12	Control of cancer cell invasion by lamin-mediated nuclear deformability Katarina Wolf (Radboud University Nijmegen Medical Centre, The Netherlands)
	13	Effect of x-irradiation on cell morphology, cytoskeleton network, and adhesion Sabato Fusco (Istituto Italiano di Tecnologia, Italy)
	14	Intracellular mechanics of normal and cancer cells Jean-Baptiste Manneville (Institut Curie, France)
	15	Higher ordered assembly of rigid biopolymers induced by depletion forces Martin Glaser (University of Leipzig, Germany)
	16	Surface tension-based model of epithelial folds Matej Krajnc (Jozef Stefan Institute, Slovenia)
	17	Mechanics of tumor growth in an in vitro model system Kristen Mills (Max Planck Institute for Intelligent Systems, Germany)
	18	Building minimal cells to understand cell shape control Mulla Yuval (FOM Institute AMOLF, The Netherlands)
	19	Cell motility at the leading edge: Measuring membrane fluctuations with an optical tweezer setup Lippoldt Jürgen (University of Leipzig, Germany)
	20	Mechanobiology of cellular trafficking across membranes Sabyasachi Dasgupta (Forschungszentrum Jülich, Germany)
	21	Polymer Physics 2.0: Exploiting programmable nanomaterials to control material properties of soft matter Carsten Schuldt (University of Leipzig, Germany)
	22	How biophysical and nanomedical tools support therapeutical improvements in neurooncology Ruiyan Zhang (Christian-Albrechts-Universität, Germany)
	23	Models for angiogenesis on microstructured surfaces Simon Schuster (LMU Munich, Germany)
	24	Composite networks of actin and intermediate filaments Tom Golde (University of Leipzig, Germany)
	25	Xenograft draining lymph nodes have alterations within the structural reticular network and collagen fibres Freja Albjerg Venning (University of Copenhagen, Denmark)
	26	Resolving the mechanobiology of the epithelium on native basement membranes Marija Plodinec (University of Basel, Switzerland)
	27	Taking the atomic force microscopy to the clinic: Predicting the prognosis and recurrence of breast cancer by integrating the nanomechanical profiles of primary tumor and its adjacent tissue Ellen Obermann (University Hospital Basel, Switzerland)
	28	Investigating cell mechanics by atomic force microscopy Alexander Dulebo (Bruker Nano Surfaces Division, Germany)
	29	Cell deformability during passage through micron-scale constrictions Janina Lange (University of Erlangen-Nuremberg, Germany)
	30	Epithelial closure dynamics Philippe Marcq (Institut Curie, France)
	31	The role of vimentin in cell migration under confinement Luiza Stankevicins (Saarland University, Germany)
	32	Cancer cell behaviours on a culture substrate imprinted with their own features Tiffany Tan (University of Otago, New Zealand)
	33	Mesenchymal migration cannot be described as a persistent random walk Charlotte Riviere (Université Lyon 1, France)
	34	New elasticity-patterned substrates for bi-dimensional organization of cells Camille Migdal (iRTSV, CEA Grenoble, France)
	35	Emergence of collective cell migration on circular micropatterns Felix Jakob Segerer (Ludwig Maximilian University of Munich, Germany)
	36	Dynamics and heterogeneity in tumor cell migration Christoph Mark (University of Erlangen-Nuremberg, Germany)

 

Session V: Cell migration in cancer
08:30 – 09:00	Active gels, cell motility and cell trajectories Raphaël Voituriez (Pierre-and-Marie-Curie University, France)
09:00 – 09:30	Tissue Engineering approaches and their relevance to studying tumor-stroma interactions Claudia Fischbach-Teschl (Cornell University, USA)
09:30 – 10:00	Toward the understanding of the growth of model epithelial tissues Ana-Suncana Smith (University of Erlangen-Nuremberg, Germany)
10:00 – 10:30	Modelling cell motility using active gel theory Rhoda J. Hawkins (University of Sheffield, UK)
10:30 – 11:00	Coffee break
11:00 – 11:30	Tumor cell migration is a superstatistical process Ben Fabry (University of Erlangen-Nuremberg, Germany)
11:30 – 12:00	Cell migration in confining spaces: pushing off the walls and squeezing through small holes Matthieu Piel (Institut Curie, France)
12:00 – 12:30	The cytoskeleton significantly impacts invasive behavior of biological cells Josef A. Käs (University of Leipzig, Germany)
12:30 – 12:45	Dynamics and heterogeneity in tumor cell migration Christoph Mark (University of Erlangen-Nuremberg, Germany)
12:45 – 13:00	Prospective end