Talks:
All talk sessions take place at Center for Biotechnology and Biomedicine (BBZ) in the large auditory (ground floor, SR 1.1 to 1.3). Contributed talks are allocated 15 min (including discussion), whereas invited talks are allocated 20 min plus 10 min discussion.

Posters:
The session for poster presentation is on Tuesday, September 24, 2013 at 17:30 at Center for Biotechnology and Biomedicine (BBZ) in the foyer. During this session snacks and fingerfood will be provided for all. The poster boards will be marked with the number according to the scientific program. Posters must fit within a rectangle 90 cm wide and 120 cm high (DIN A0), portrait format. The material necessary to mount the poster (pins or "Poster Strips") will be provided.

 

14:00 – 14:15	Welcome / Opening Josef A. Käs (University of Leipzig, Germany)
Session I: Mechanical properties of cancer cells and the tumor microenvironment
14:15 – 14:45	The physical bounds of in vivo cell motility Josef A. Käs (University of Leipzig, Germany)
14:45 – 15:15	Trafficking, sorting, and differentiation in relation to nuclear rheology Dennis E. Discher (University of Pennsylvania, USA)
15:15 – 15:45	Elasticity at the edge of stabilty: network mechanics and response to stress Fred MacKintosh (VU University Amsterdam, Netherlands)
15:45 – 16:15	Coffee break
16:15 – 16:45	Novel growth regime of MDCK II model tissues on soft substrates Sara Kaliman (University of Erlangen, Germany)
16:45 – 17:15	Nuclear architecture, mechanics and movements Kris Noel Dahl (Carnegie Mellon University, USA)
17:15 – 17:45	Muhammad Zaman (Boston University, USA)
17:45 – 18:00	Keratins are major determinants of migration and invasion by regulating adhesion and cell stiffness Kristin Seltmann (University of Leipzig, Germany)
Poster Session
18:00 - 20:00	01	Keratins are major determinants of migration and invasion by regulating adhesion and cell stiffness Kristin Seltmann (University of Leipzig, Germany)
	02	Centrosome positioning during Epithelial to Mesenchymal Transition Mithila Burute (Cytoo, Grenoble, France)
	03	Elasticity and the shape of prevascular solid tumors Kristin Mills (Max Planck Institute for Intelligent Systems, Germany)
	04	Cancer metastasis: collective invasion and cell guidance in multicellular systems Adrien Hallou (University of Cambridge, UK)
	05	Optimality of force transmission in a motor-clutch cellular adhesion model Benjamin Bangasser (University of Minnesota, USA)
	06	Identifying malignant melanoma through unique signatures in blood flow dynamics Gemma Lancaster (Lancaster University, UK)
	07	High resolution magnetic resonance elastography of the in vivo human brain: Application to presurgical mechanical characterization of glioblastoma Jing Guo (Charite-University Medicine Berlin, Germany)
	08	Challenges in probing cellular adhesion forces using atomic force microscopy Steve Pawlizak (University of Leipzig, Germany)
	09	Diffusive transport and spontaneous vortex formation in cell sheets invading µ-structured channels Matthias Zorn (Ludwig Maximilian University of Munich, Germany)
	10	DNA nanostructures as carriers of therapeutic biomolecules Jessica Lorenz (Fraunhofer Institute for Cell Therapy and Immunology, Germany)
	11	High contrast visualization of cell-hydrogel contact by advanced interferometric optical microscopy Takahisa Matsuzaki (University of Saitama, Japan)
	12	Surface tension governs the shape of mechanically confined cells in mitosis Elisabeth Fischer-Friedrich (Max Planck Institute for the Physics of Complex Systems, Germany)
	13	Tracking of single cell migration in engineered 3D microenvironments Jiranuwat Sapudom (University of Leipzig, Germany)
	14	Tension homeostasis of epithelial cells by surface area regulation: Model and application Bastian Rouven Brückner (Georg August University of Göttingen, Germany)
	15	The 3D vertex model for epithelial mechanics Silvanus Alt (Max Planck Institute for the Physics of Complex Systems, Germany)
	16	Quantitative evaluation of cancer cell adhesion to organosilane monolayer by reflection interference contrast microscopy Kosaku Ito (University of Saitama, Japan)
	17	Damir Vurnek
	18	How are intermediate filaments integrated into cellular structures by synemin and nestin? Petra Zugschwerdt (German Cancer Research Center, Germany)
	19	Nanomechanics of basement membrane invasion under hypoxic conditions - reenacting metastasis in vitro P. Oertle (Biozentrum and the Swiss Nanoscience Center, Switzerland)
	20	Entropic contraction of actin networks Carsten Schuldt (University of Leipzig, Germany)
	21	Fluorescent Beads Disintegrate Actin Networks Tom Golde (University of Leipzig, Germany)
	22	The generation of topological order in the nuclear lamina studied with GFP-lamin A Kendra Maaß (German Cancer Research Center, Germany)
	23	Temperature Induced Sudden Loss of Cell Nuclei Integrity Enrico Warmt (University of Leipzig, Germany)
	24	Entropic contraction of actin bundles Jörg Schnauß (University of Leipzig, Germany)
	25	Refractometry of single, suspended biological cells in a dual-beam optical trap Steffen Grosser (University of Leipzig, Germany)

 

Session II: Cell-cell and cell-matrix adhesions in cancer
08:30 – 09:00	Jens Elgeti (Forschungszentrum Jülich, Germany)
09:00 – 09:30	Ana J. García Sáez (German Cancer Research Center & BioQuant & Max Planck Institute for Intelligent Systems, Germany)
09:30 – 10:00	Cross talk of melanoma cells and peritumoral fibroblasts influences melanoma proliferation Ulf Anderegg (University of Leipzig, Germany)
10:00 – 10:30	Coffee break
10:30 – 11:00	Arnoud Sonnenberg (Netherlands Cancer Institute, Germany)
11:00 – 11:30	Luke Casserau (University of California, San Francisco, USA)
11:30 – 12:00	Rudolf Merkel (Forschungszentrum Jülich, Germany)
12:00 – 12:15	Centrosome positioning during Epithelial to Mesenchymal Transition Mithila Burute (Cytoo, Grenoble, France)
12:15 – 12:30	Elasticity and the shape of prevascular solid tumors Kristin Mills (Max Planck Institute for Intelligent Systems, Germany)
12:30 – 14:30	Lunch break
Session III: Mechanics of cell adhesion and cytoskeletal dynamics in cancer
14:30 – 15:00	Intravital tissue imaging of collective tumor cell invasion: interface guidance and resistance niches Bettina Weigelin (Radboud University Nijmegen, Netherlands)
15:00 – 15:30	Mechanistic principles of the nuclear lamina: How is lamin assembly generating tough geodesic structures and why do the four lamins segregate? Harald Herrmann (German Cancer Research Center, Germany)
17:00	Get together for invited speakers (boat, "Stelzenhaus")

 

Session IV: Mechanics of single cell and collective migration during malignant cancer progression
08:30 – 09:00	Cell migration through narrow pores: matrix mechanics versus geometry Ben Fabry (University of Erlangen, Germany)
09:00 – 09:30	Ulrich Schwarz (University of Heidelberg, Germany)
09:30 – 10:00	The importance of being well rounded Buzz Baum (University College London, UK)
10:00 – 10:30	Coffee break
10:30 – 11:00	Signalling in the tumour microenvironment: Essential roles for extracellular ADAM proteases in malignant tumours Jörg W. Bartsch (University Marburg, Germany)
11:00 – 11:30	Robert H. Austin (Princeton University, USA)
11:30 – 12:00	Xavier Trepat (University of Barcelona, Spain)
12:00 – 12:15	Cancer metastasis: collective invasion and cell guidance in multicellular systems Adrien Hallou (University of Cambridge, UK)
12:15 – 12:30	Optimality of force transmission in a motor-clutch cellular adhesion model Benjamin Bangasser (University of Minnesota, USA)
12:30 – 14:30	Lunch break
Session V: Role of the endothelium in cancer disease
14:30 – 15:00	Rudolf Leube (RWTH Aachen University, Germany)
15:00 – 15:30	Rodger D. Kamm (Massachusetts Institute of Technology, USA)
15:30 – 16:00	Melody A. Swartz (Ecole Polytechnique Federale de Lausanne, Switzerland)
16:00 – 16:30	Franziska Lautenschläger (Saarland University, Germany)
16:30 – 17:00	Macromolecular protein complexes in Wnt signalling Jürgen Behrens (University of Erlangen, Germany)
17:00 – 17:30	Matthias Rief (Technical University Munich, Germany)
19:00	Get together for invited speakers ("Gewandhaus")

 

Session VI: Biomechanics and tumorigenesis
08:30 – 09:00	Markus Löffler (University of Leipzig, Germany)
09:00 – 09:30	Marija Plodinec (University of Basel, Switzerland)
09:30 – 09:45	Identifying malignant melanoma through unique signatures in blood flow dynamics Gemma Lancaster (Lancaster University, UK)
09:45 – 10:00	High resolution magnetic resonance elastography of the in vivo human brain: Application to presurgical mechanical characterization of glioblastoma Jing Guo (Charite-University Medicine Berlin, Germany)
10:00 – 10:45	Coffee break
10:45 – 11:15	Michael Murrell (University of Chicago, USA)
11:15 – 11:45	Mechanosensing with primary cilia Christoph F. Schmidt (University of Göttingen, Germany)
11:45 – 12:15	Molecular dissection of lamellipodium protrusion Klemens Rottner (University of Bonn, Germany)
12:15 – 12:45	Pressure and stiffness sensing in glioma cells Paul Janmey (University of Pennsylvania, USA)
12:45 – 13:00	Prospective end