8th Annual Symposium
Physics of Cancer
Leipzig, Germany
October 4-6, 2017
Contributed Talk
Electron irradiated hydrogels: Reagent-free modification towards biomedical applications
Stefanie Riedel1,2, Stefan G. Mayr1,2
1University Leipzig, Linnéstraße 5, 04103 Leipzig
2IOM Leipzig e.V., Permoserstr. 15, 04318 Leipzig
The hydrogels collagen and gelatin have attracted considerable interest in biology and medicine during the past years. Due to their strong biocompatibility and biodegradability, they are highly attractive materials for biomedical applications such as extracellular matrix components. Thereby, adaptation of structure and mechanics as well as stimuli-response is an interesting aspect of the modification of these materials. Reagent-free modification of hydrogels can be achieved by utilizing high energy irradiation e.g. electron irradiation to crosslink.
We will demonstrate how crosslinking with high-energetic electrons allows fine-tuning of materials properties such as structure and mechanics. Furthermore, we will present the development of stimuli-responsive systems as well as topographically and mechanically patterned hydrogel substrates for biomedical applications.
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